Compliance and persistence with osteoporosis therapies: we can do better
نویسندگان
چکیده
Deborah T Gold† & Stuart L Silverman †Author for correspondence Duke University Medical Center, Departments of Psychiatry and Behavioral Sciences, and Sociology, Center for Aging, Box 3003, Durham, NC 27710, USA Tel.: +1 919 660 7530; Fax: +1 919 668 0453; [email protected] ‘The aging of the US population virtually guarantees that the prevalence of osteoporosis and the incidence of related fractures will both skyrocket.’
منابع مشابه
Two-year persistence and compliance with osteoporosis therapies among postmenopausal women in a commercially insured population in the United States
This retrospective, observational study assessed 2-year persistence and compliance by treatment, route of administration, and dosing frequency in postmenopausal women initiating a new osteoporosis therapy. Two-year persistence and compliance rates were higher in women receiving injectables compared with oral agents. PURPOSE This study extends previous studies limited to 1-year follow-up by ex...
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BACKGROUND Poor adherence with oral bisphosphonates (BPs) can mitigate their therapeutic benefit for osteoporosis and is a significant clinical burden. Most previous studies regarding adherence with oral BPs have focused on postmenopausal osteoporosis, but little attention has been given to patients with rheumatoid arthritis (RA). Thus, we investigated compliance and persistence with oral BPs i...
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BACKGROUND Prior research has shown that rates of persistence and compliance with osteoporosis therapies are associated with significantly fewer vertebral, nonvertebral, and hip fractures. A number of studies have examined medication-taking behavior with oral bisphosphonates and teriparatide, and these 1-year persistence rates have ranged from 39.9% to 56.7%. Limited real-world data are availab...
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Adherence to medications is poor and suboptimal in many chronic diseases. Nonadherence can reduce treatment effectiveness and can have an impact on healthcare costs. As a consequence, it may alter the cost-effectiveness of drug therapies. This article emphasizes the importance of integrating medication compliance and persistence into pharmacoeconomic evaluations, using osteoporosis as an exampl...
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UNLABELLED Compliance and persistence with daily, weekly, and monthly bisphosphonates (BPs) for osteoporosis were assessed using data from the Platform for Clinical Information Statistical Analysis (CISA) database that contains data of prescriptions in 13 university hospitals in Japan. The analysis revealed compliance and persistence improved as the dosing interval increases. PURPOSE BPs are ...
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